Current Issue

Vol. 1 No. 1 (2025)
Published November 16, 2025
Cardiology

We are publishing a series of meta-analysis in cardiology.

More

Meta-analysis

Laiba Khan, Maham KHAN, Mahmood Ahmad, Muhammad Hamza KHAN, Joanne Lac
Forecasting National Non-Communicable Disease Mortality Using Machine Learning: An Ecological Study of Predictive Factors: Machine Learning
Paper
Laiba Khan, Maham KHAN, Mahmood Ahmad, Muhammad Hamza KHAN, Joanne Lac
786-MIII RR/OR NMA: An Interactive R Shiny App for Conducting Frequentist Network Meta-Analysis of Ratio Outcomes: Conducting Frequentist Network Meta-Analysis of Ratio Outcomes
Full paper
Poe Hnin Phyu, Mahmood Ahmad, Laiba Khan, Maham Khan, Nijat Rizayev, Manpreet Kour, Touqeer Rana, Andrew Woo, Parichatra Homhuan
The Identifying a New Typology of European Health Systems
PDF
Niraj S Kumar, Ruhani Singh, Mahmood Ahmad
FragilitySynth: Deconstructing the Coronary Sinus Reducer Controversy via Systems Engineering and Bayesian Decision Theory
manuscript html
Laiba Khan, Mahmood Ahmad, Maham Khan, Muhammad Hamza Khan, Joanne Lac
Transcatheter Treatment for Severe Symptomatic Tricuspid Regurgitation: A Rapid Meta-Analysis of Randomised Evidence (2025): A Rapid Meta-Analysis of Randomised Evidence (2025)
pdf

Methods notes

Tia Mistry, Mahmood Ahmad, Igor Buslowski
The Revascularisation Paradox: Statistical Fragility in the 2024 JACC Meta-Analysis: Methodological Critique & Simulation Synthesis
manuscript
Khaing Mar Lwin, Mahmood Ahmad, Tomi, Ata Ul Hayee Sohail
A Stochastic Approach to LDL-C Intensification
manuscript manuscript
ma6y ma6y; Andrew Woo
C-STREAM: A new meta-analysis engine for Transportability
html file
View All Issues

Welcome to Synthēsis
Synthēsis publishes concise, transparent, and reproducible meta-analyses across all areas of medicine.
Each paper is limited to 400 words (excluding tables and references) and must include open data, analysis code, and a registered protocol.

Our mission
To improve the quality and clarity of evidence synthesis through strict reporting standards (PRISMA, RoB, GRADE) and open-science practices.

Article types

  • Short Meta-analyses

  • Methods Notes

  • Brief Updates

Licensing
All articles are published Open Access under the Creative Commons Attribution 4.0 International (CC BY 4.0) licence.
Data are released under CC0 and code under MIT or Apache-2.0 licences.