Synthēsis is an open-access journal dedicated to concise, transparent, and reproducible meta-analyses across all areas of medicine. The journal publishes short-format reports (typically ≤1,000 words, excluding tables and references) that prioritise methodological rigour, interpretability, and openness.

All articles are published under the Creative Commons Attribution 4.0 International (CC BY 4.0) licence. Data are shared under CC0, and code under MIT or Apache-2.0 licences, ensuring full reproducibility and reusability.

Each submission must include a pre-registered protocol (e.g., PROSPERO or OSF), a complete PRISMA 2020 flow diagram, appropriate risk-of-bias assessment (RoB 2, ROBINS-I), and a GRADE summary of evidence. Studies are expected to report heterogeneity metrics (I², τ², prediction intervals) and provide open datasets and code repositories with DOIs.

Synthēsis operates a single-anonymous peer-review process focused on transparency and educational value for first-time meta-analysis authors.

Archiving and Access
The journal’s contents are preserved through the PKP Preservation Network (PN) and LOCKSS/CLOCKSS. All published articles are indexed and archived in PubMed Central (application in progress).

Privacy and Ethics
Author and reviewer data are handled in accordance with international privacy standards and the COPE Core Practices.