Technology Transfer & Capacity Building: A Forensic Audit of Clinical Trial Equity in Uganda

Beyond the Extractive Paradigm: Implementing a Build-and-Stay Philosophy for Sovereign Research

Authors

  • Chikosa Kumbukani
  • Michael Bosiako Antwi
  • Christine Muhumuza
  • Njeodo Njongang Vigny
  • Fadumo Said Hassan
  • Ruchius Philbert
  • Rhoda Chikula
  • Amina Mohamud Fidow
  • Shamim Nabidda
  • Bruce Tukamushaba
  • Ronnie Ssenfuma Christian
  • Adrine Nyamwiza
  • Bitness Lyabagaga
  • Alice Namiiro Martha
  • Joy Osifo
  • Edith Kanyesigye
  • Natinael Berhane yeshanew
  • Justine Kirabo
  • Felix Awuriki Kofi
  • Joanitah Namatovu
  • Olivia Amumpaire

DOI:

https://doi.org/10.66040/27x7fb10

Keywords:

Health Informatics, Clinical Trial Equity, Technology Transfer, OpenMRS, Uganda, Research Sovereignty, Gini Coefficient

Abstract

This article presents a forensic audit of 23,873 clinical trial registrations to investigate the disparity between research volume and local infrastructure investment in Africa. The analysis reveals a Gini coefficient of 0.809, indicating extreme inequality where 99.6% of trials bypass permanent technology transfer. Focusing on the Ugandan context, the study highlights that while the nation hosts 809 interventional trials with a positive performance residual of +1.43, implementation of tools like the OpenMRS SDK at district facilities such as Mukono General and Kawolo Hospital remains an afterthought. The author argues for a transition from hosting research to owning discovery through ethical funding mandates that prioritize permanent capacity building. By adopting a "build-and-stay" philosophy, the research community can ensure that national health sovereignty is preserved through the local maintenance and ownership of clinical digital infrastructure.

Author Biography

  • Ronnie Ssenfuma, Christian

    Master's Student in Health Informatics
    Makerere University

    School of Public Health

References

1. Sewankambo, N. K., et al. (2015). "Enabling health research capacity in Africa: the Makerere University experience." Global Health Action.

2. Lang, T. A., et al. (2023). "The Global Health Network: local leadership in clinical trials." The Lancet Global Health.

3. Wagstaff, A., et al. (1991). "On the measurement of inequality in health." Journal of Health Economics.

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Published

2026-04-12 — Updated on 2026-06-16

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Research Article

How to Cite

Technology Transfer & Capacity Building: A Forensic Audit of Clinical Trial Equity in Uganda: Beyond the Extractive Paradigm: Implementing a Build-and-Stay Philosophy for Sovereign Research. (2026). Synthēsis, 2(3). https://doi.org/10.66040/27x7fb10 (Original work published 2026)

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