Vol. 2 No. 5: July 2026

Published: 2026-07-01

E156 Research Letter

WHO Alignment and Disease Burden Gaps

Michael Bosiako Antwi, Njeodo Njongang Vigny , Shamim Nabidda , Tukamushaba Bruce , Christine Muhumuza , Fadumo Said Hassan , Ssenfuma Ronnie
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Beyond the Gap: 80% Use, 0.0% Trials — The Traditional Medicine Research Void Across Africa Traditional Medicine Integration

Grace Kemigisha, Anna Nakhabi, Evelyn Nakuya, Peter Eyong Ebot, Mohammad Murtala Yusuf; Gloria Margaret Nanono
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The Antimicrobial-Resistance “Trial Deficit” in Africa, Re-examined: Why the Headline Statistic Fails and What the Real Gap Is Antimicrobial Resistance Crisis

Gloria Margaret Nanono, Christopher Tibamwenda, Jacob Muruhukye, Grace Kemigisa, Peter Ebot Eyong, Fiona Obbo, Prossy Nabateregga
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Dynamics of Zoonotic Disease at the One Health Interface: Evidence from a Systematic Review

Nakhabi Anna, Jacob Muruhukye, Eleanor Sabuka, Christopher Tibamwenda, Lauritta Chinazaekpere Ndufeiya, Gloria Margaret, Nanono, Nwanja Olive Ebere
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Assessment of PEPFAR Funding Reduction on the Quality of HIV Services at Sex Workers Outreach Program Clinics, Nairobi County, Kenya

Idah Mirera, Caroline Kawila, Jonathan Monda
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Informed Consent Language and Structural Inequity in African Clinical Trial Governance: A Cross-Sectional Audit

Musoke Muhammad, Ivan Mutyaba, Huzaifah Mutyaba, Tom Okade, Martina Uisso, Shamim Nabidda, Ssenfuma Ronnie
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Artificial Intelligence in Clinical Trials: A Cross-Sectional Analysis of Structural Inequities in African and United States Research Investment

Frank Matovu, Lauryn Nsenga, Simachew Getaneh Endalamew, Mary Nafuna
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Precision Medicine in Africa: A Systematic Review of Genomic Resilience and Structural Gaps

Muruhukye Jacob, Eleanor Sabuka, Anna Nakhabi, Mukisa Paul Brian, Nanono Gloria Margaret, Nabateregga Prossy, Eyong Peter Ebot
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Geographic Inequity in African Clinical Trials: A Systematic Review Evidence of a Port-City Advantage

John Kokas Obwiin
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Sample Size Adequacy Audit

Joy Osifo
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Inequities in Clinical Trial Distribution for Neglected Tropical Diseases: A Cross-Sectional Analysis of Global Research Concentration

Ronald Bwambale, Mutebi, Nelson Nsubuga, Janepher Nabaasa, Aggrey Gavamukulya, Persis Tikabulamu, Phiona Obbo
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Global CVD Trends and Regional Risk‐Profile Clustering Using GBD 2022 Data Global CVD Trends

Laiba Khan, Maham Khan, Muhammad Hamza Khan, Joanne Lac
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Community advisory structure in African clinical trials: A registry-based analysis

Peter Eyong Ebot, Jacob Muruhukye, James Mukiibi, Spritney Nashua Ninpa , Christopher Tibamwenda, Meldwinel Ayuk , Prossy Nabateregga
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HIV Trial Saturation Index

Idah Mirera, Everlyne Nakuya, Nabaasa Janepher, Eyong Ebot, Fadumo Hassan
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The PLATO trial - was it too good to be true?

Daniel Coles
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Reappraising Evidence for Intravascular Imaging–Guided PCI

Majed Sheikh
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SGLT2 Inhibitors in Heart Failure: Living Meta-Analysis Across the EF Spectrum

Hamood Saeed
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TruthCert: A Fail-Closed Certification Protocol for LLM Outputs in Evidence Synthesis

Ronnie Ssenfuma
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SGLT2 Inhibitors and Heart Failure Outcomes Across the Ejection Fraction Spectrum; a Systematic Review and Meta-Analysis

John Kokas Obwiin
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CardioOracle: Predicting Cardiovascular Trial Outcomes Using Bayesian Historical Borrowing and Design Feature Analysis

Syed Muhammad Ali
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RoBVisShiny: An Interactive R Shiny Application for Visualizing Risk-of-Bias Assessments

Laiba Khan, Maham Khan, Muhammad Hamza Khan, Joanne Lac
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